Drug eruption - Narkootikumide Purse
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Saksamaa 2022. aasta Stiftung Warentesti tulemustes oli tarbijate rahulolu ModelDermiga vaid veidi madalam kui tasuliste telemeditsiini konsultatsioonidega.
Saksamaa 2022. aasta Stiftung Warentesti tulemustes oli tarbijate rahulolu ModelDermiga vaid veidi madalam kui tasuliste telemeditsiini konsultatsioonidega.
Narkootikumide purse (Drug eruption) iseloomustab kogu keha mõjutamist.
relevance score : -100.0%
ReferencesRavimitest põhjustatud nahareaktsioonid, mida nimetatakse ravimipurseteks, võivad mõnikord olla rasked. Neid raskeid reaktsioone, mida nimetatakse severe cutaneous adverse drug reactions (SCARs), peetakse eluohtlikeks. Nende hulka kuuluvad sellised seisundid nagu Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP) ja drug reaction with eosinophilia and systemic symptoms (DRESS). Kuigi SCARs on haruldane, esineb neid ligikaudu 2 % haiglas viibivatest patsientidest.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
31-aastane naine külastas nahahaiguste osakonda valutu punase laiguga parema jalal ülaosas. Ta võttis eelmisel päeval ühe annuse doksütsükliini (100 mg) pärast aknearmide pikosekundilist laserravi. Eelmisel aastal koges ta samasugust probleemi samal kohal pärast sama annuse doksütsükliini manustamist laserravi järel. Tal ei ole olulist haiguslugu ega muid sümptomeid, nagu palavik, ei lokaalselt ega kogu kehas.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
Stevens-Johnson syndrome (SJS) ja toxic epidermal necrolysis (TEN) on kaks tõsist nahareaktsiooni, mis erinevad teistest nahahaigustest, nagu multiformne erüteem ja stafülokoki põletatud naha sündroom, ning ka ravimireaktsioonidest. SJS/TEN on haruldane ja raske reaktsioon, mis põhjustab naha ja limaskestade ulatuslikke kahjustusi, sageli süsteemsete sümptomitega. Üle 80 % juhtudest on põhjuseks ravimid.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Narkootikumide lööbeid diagnoositakse peamiselt haigusloo ja kliinilise läbivaatuse põhjal. Kasulikud võivad olla naha biopsia, vereanalüüsid või immunoloogilised testid.
Levinud purset põhjustavad ravimid on näiteks antibiootikumid ja muud antimikroobsed ravimid, sulfaravimid, mittesteroidsed põletikuvastased ravimid (MSPVA-d), pahaloomuliste kasvajate keemiaravi ained, krambivastased ained ja psühhotroopsed ravimid.
○ Diagnostika ja ravi
Kui teil on palavik (kehatemperatuuri tõus), pöörduge võimalikult kiiresti arsti poole. Kahtlustatava ravimi kasutamine (nt antibiootikumid, mittesteroidsed põletikuvastased ravimid) tuleb katkestada. Enne haiglasse pöördumist võivad suukaudsed antihistamiinikumid, nagu tsetirisiin või loratadiin, leevendada sügelust ja lööbeid.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]
Vereanalüüs (CBC, LFT, eosinofiilide arv).
Suukaudsed steroidid ja antihistamiinikumid, mis määratakse arsti retsepti alusel.